Human papillomavirus 5 and 8 E6 downregulate interleukin-8 secretion in primary human keratinocytes

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Human papillomavirus 5 and 8 E6 downregulate interleukin-8 secretion in primary human keratinocytes.

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Interleukin-5 modulates interleukin-8 secretion in eosinophilic inflammation.

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Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.

Papillomaviruses possess small DNA genomes that encode five early (E) proteins. Transient DNA replication requires activities of the E1 and E2 proteins and a DNA segment containing their binding sites. The E6 and E7 proteins of cancer-associated human papillomavirus (HPV) transform cells in culture. Recent reports have shown that E6 and E7 are necessary for episomal maintenance of HPV in primar...

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Chapter 8: Human papillomavirus and skin cancer.

A high prevalence of human papillomavirus (HPV) DNA, particularly in squamous cell skin carcinoma of immunosuppressed but also of immunocompetent patients, has renewed great interest in a possible etiologic role of HPV in nonmelanoma skin cancer. It is difficult, however, to interpret these findings against a background of low-level infections with multiple HPV types from supergroup B (HPV4-rel...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 2009

ISSN: 0022-1317,1465-2099

DOI: 10.1099/vir.0.016527-0